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Mental Health Mission Mood Disorder Cohort Study

13 August 2026

About the study

The Mental Health Mission Cohort is a study collecting data from a group of people (a “cohort”) who have (or have a history of) depression that has been difficult to treat or who have bipolar disorder.

We would like to increase our understanding of these illnesses with the aim of improving the lives of people experiencing depression and bipolar disorder.

The study aims to :

  • Give people with depression the best opportunity to take part in research studies
  • Give researchers controlled access to research data from a large number of people so they can ask questions such as why do some people respond to treatments and others don’t
  • Use the data to help to develop more effective treatment approaches

The study aims to involve up to 2000 patients aged 18 years or over who have received a clinical assessment of a mood disorder.

What does the study involve?

  • Participants in the study are asked permission to share details of a clinical assessment completed within the Care Pathway Enhancement (CaPE) Clinic or within a secondary care team. These details are added to the study database.
  • Participants are asked to complete a set of questionnaires including information on demographics, mental health, emotional wellbeing and quality of life. This can be done via a telephone or video call if preferred.

Participants are given the option to participate in additional research activities:

  • Online learning and thinking tasks
  • Follow up questionnaires every 3 months
  • An option to join the Genetic Links to Anxiety and Depression (GLAD) Study
  • An option to link your study data to other databases, for example GP or secondary care records

What are the possible benefits of taking part?

  • We hope that the information that you provide will help us to develop more effective approaches to clinical care and treatments and to improve longer-term care for people with depression or bipolar disorder.
  • By completing questionnaires via online methods, you will be able to see displays of your questionnaire responses over time and this may be helpful for you. If you wish, you can share these with your clinician.
  • If you wish to be contacted, the data provided will help the study team to identify further research opportunities which might be of interest to you.

Who can take part

People who are over the age of 18 years who have (or have a history of) depression that has been difficult to treat or who have bipolar disorder.

Interested in taking part or would like further information? Please contact:

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