The studies listed below are being conducted at Newcastle University, with links to NCMD. They are ongoing and from time to time need people to take part in them. Where this is the case, there is a link showing how you can get involved.
The LQD study is investigating which of two medications (lithium or quetiapine) added to an antidepressant is best in helping people with treatment resistant depression.Read more
The BRIGhTMIND study is looking at the effectiveness of a new approach to treat treatment resistant depression (TRD) using pulses of magnetic stimulation applied to the scalp.
The Psilocybin Study is a multi-centred worldwide clinical
trial examining the safety and efficacy of psilocybin (the ‘magic’ in ‘magic
mushrooms’) in participants with treatment resistant depression.
PAX-BD is a major trial investigating the effectiveness and safety of a drug, pramipexole, which is currently used to treat Parkinson’s Disease, for patients with treatment resistant bipolar depression.Read more
Lithium can effectively treat and prevent mania and depression, as well as reduce risk of suicide. However, it does not work for everyone. The BLISS is examining why lithium is an effective treatment for some patients with bipolar disorder but not others, using magnetic resonance techniques.
The RESTORE-LIFE study looking at the effectiveness and efficiency of Vagus Nerve Stimulation (VNS) in difficult to treat patients with depression.Read more
The ALFI study is examining the psychometric properties of a newly developed questionnaire (“ALFI”) in a sample of typically developing young people aged 16-25 years, to more accurately measure adaptive functioning in this population.
EPICC-ID is a trial evaluating the clinical and cost effectiveness of a parenting group, Level 4 Stepping Stones Triple P (SSTP), designed to reduce challenging behaviour in preschool children with a moderate to severe intellectual disability.
The EOD-UK & ROI study is investigating the incidence of first time diagnosis, management, clinical presentations, and outcome for children diagnosed with Early Onset Depression.
The CAPMEM study is exploring whether the autonomic nervous
system works differently in people with mental health, neurodevelopmental, and
neurodegenerative disorders and whether this explains the memory and
concentration problems in these populations.
Clinicians have worked collaboratively with young people and their families to develop an App for mood monitoring for young people aged 15-25 years with Early Onset Bipolar Disorder.