Current studies

The COMP 006 study explores the delivery of an investigational medicine (COMP360) alongside psychological support for the treatment of depression which has not responded to antidepressant treatment.

ASCEnD is a clinical and cost-effectiveness study of aripiprazole combined with sertraline for patients with bipolar depression. It is running in 10 sites across the UK and recruitment is open now!

The SCiD study is looking at how sleep affects the brain and cognition in patients ages 18-65 with a diagnosis of depression.

Randomised placebo-controlled trial evaluating the efficacy and mechanism of pramipexole as add-on treatment for people with treatment resistant depression.

R-LiNK is an EU-funded, multicentre longitudinal observational study that aims to determine which individuals with bipolar I disorder are most eligible for long-term lithium treatment in terms of response, safety and tolerability.

Clinicians have worked collaboratively with young people and their families to develop an App for mood monitoring for young people aged 15-25 years with Early Onset Bipolar Disorder.

The CAPMEM study is exploring whether the autonomic nervous system works differently in people with mental health, neurodevelopmental, and neurodegenerative disorders and whether this explains the memory and concentration problems in these populations.

The ALFI study is examining the psychometric properties of a newly developed questionnaire (“ALFI”) in a sample of typically developing young people aged 16-25 years, to more accurately measure adaptive functioning in this population.

The RESTORE-LIFE study looking at the effectiveness and efficiency of Vagus Nerve Stimulation (VNS) in difficult to treat patients with depression.

The EOD-UK & ROI study is investigating the incidence of first time diagnosis, management, clinical presentations, and outcome for children diagnosed with Early Onset Depression.

EPICC-ID is a trial evaluating the clinical and cost effectiveness of a parenting group, Level 4 Stepping Stones Triple P (SSTP), designed to reduce challenging behaviour in preschool children with a moderate to severe intellectual disability.