Current studies
The studies listed below are being conducted at Newcastle University, with links to NCMD. They are ongoing and from time to time need people to take part in them. Where this is the case, there is a link showing how you can get involved.
COMBINER
The effectiveness of Lithium plus Quetiapine COMBination versus LithIum versus QuetiapiNe monothErapy in the maintenance treatment of bipolaR disorder: the COMBINER trial.
Read moreALTO-100-211
A randomised, double-blind, placebo-controlled study followed by open-label treatment of ALTO-100 in adults with bipolar disorder currently experiencing a Major Depressive Episode
Read moreHOME
HOME is a study of transcranial direct current stimulation in major depression across 6 centres
Read moreHELIOS-BD
Lithium's mechanism in bipolar disorder: Investigating the light hypersensitivity hypothesis
Read moreSupplemental Lithium Imaging, Peripheral Inflammation and Mitochondrial Function (SLIPI-M) study
The SLIPI study will measure the effects of lithium orotate on peripheral biomarkers of inflammation and mitochondrial function on healthy male volunteers aged 18-65 years old.
Read moreCognitive Remediation in Bipolar (CRiB2)
CRiB2 is a study which aims to investigate whether cognitive remediation therapy is effective in improving the thinking skills and daily life functioning of people with bipolar disorder.
Read moreCOMP 006
The COMP 006 study explores the delivery of an investigational medicine (COMP360) alongside psychological support for the treatment of depression which has not responded to antidepressant treatment.
Read moreASCEnD
ASCEnD is a clinical and cost-effectiveness study of aripiprazole combined with sertraline for patients with bipolar depression. It is running in 10 sites across the UK and recruitment is open now!
Read moreEffectiveness and efficiency of VNS Therapy as adjunctive therapy in patients with difficult to treat depression (RESTORE-LIFE)
The RESTORE-LIFE study looking at the effectiveness and efficiency of Vagus Nerve Stimulation (VNS) in difficult to treat patients with depression.
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