Major Depressive Disorder (MDD) is also known as depression. It is a mental disorder characterised episodes of low mood lasting at least two weeks...Read more
Major Depressive Disorder (MDD) affects 350 million individuals world‐wide. While antidepressants can be very effective for many people, as many as a third remain unwell after several adequate trials of antidepressants...
Psychedelics are believed to exert their effect via serotonin receptors called 5‐HT1A/2A. Common effects reported include alterations of sensory perception, ego loss, an increased awareness of the present...Read more
ECT was first introduced to treat depression in 1938. The stigma attached to ECT is based on early treatments when the patients were awake when relatively high doses of electricity were administered...Read more
The effects of exercise are multiple and varied and include the ability to alleviate depressive symptoms and to enhance the production of new neurons (neurogenesis)...Read more
The hypothalamic‐pituitary‐adrenal axis is part of the neuroendocrine system and has been shown to be a critical regulator of the stress response...Read more