The studies listed below are being conducted at Newcastle University, with links to NCMD. They have already been completed.
Bipolar Lithium Imaging and Spectroscopy Study (BLISS)
Lithium can effectively treat and prevent mania and depression, as well as reduce risk of suicide. However, it does not work for everyone. The BLISS is examining why lithium is an effective treatment for some patients with bipolar disorder but not others, using magnetic resonance techniques.Read more
Sleep Problems in Bipolar Disorder
This study assessed sleep in patients with bipolar compared to healthy patients. It was found that patients with bipolar disorder had high rates of sleep problems, including insomnia, over-sleeping, obstructive sleep apnoea, and inconsistent patterns of going to sleep and waking up.Read more
Electroconvulsive therapy (ECT) is an effective treatment for depression but has many side effects, particularly memory problems. This study explored whether ketamine may protect against memory problems from ECT. The results showed that ketamine made no difference to the beneficial effect of ECT.Read more